http://methadoneuses.com/methadone-uses/270/which-prescription-medication-is-stronger-morphine-or-methadone/ Comprehensive Information About the Uses of Methadone Sat, 03 Oct 2009 11:08:42 -0500 http://wordpress.org/?v=2.8.2 hourly 1 http://methadoneuses.com/methadone-uses/270/which-prescription-medication-is-stronger-morphine-or-methadone/comment-page-1/#comment-578 W W D Mon, 03 Aug 2009 22:35:34 +0000 http://methadoneuses.com/methadone-uses/270/which-prescription-medication-is-stronger-morphine-or-methadone/#comment-578 It's complicated on a number of points, so I wouldn't advise a simple substitution. Roughly (very roughly) two thirds of morphine is "lost" to first-pass metabolism through the liver when taken orally, so the Kadian won't be quite as much on a milligram-for-milligram basis, but the exact ratio is impossible to predict with good accuracy. Methadone 20 mg is roughly equivalent to 10 parenteral morphine, but again there's lots of individual variation. It’s complicated on a number of points, so I wouldn’t advise a simple substitution. Roughly (very roughly) two thirds of morphine is “lost” to first-pass metabolism through the liver when taken orally, so the Kadian won’t be quite as much on a milligram-for-milligram basis, but the exact ratio is impossible to predict with good accuracy. Methadone 20 mg is roughly equivalent to 10 parenteral morphine, but again there’s lots of individual variation.

]]> http://methadoneuses.com/methadone-uses/270/which-prescription-medication-is-stronger-morphine-or-methadone/comment-page-1/#comment-577 mercedesofladies36 Sun, 02 Aug 2009 17:42:58 +0000 http://methadoneuses.com/methadone-uses/270/which-prescription-medication-is-stronger-morphine-or-methadone/#comment-577 methadone....it killed anna nicole for christ sake as well as her son|!@ methadone….it killed anna nicole for christ sake as well as her son|!@

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