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which prescription medication is stronger, Morphine or Methadone?

perryinjax asked:

Hi,
What is stronger, 20mg of methadone or a 20mg Kadian capsule? (Kadian is supposed to be some kind of Morphine time release capsule)
If someone is used to taking 100mg of Methadone per day, then will a 20mg Kadian capsule, even crushed up, have any noticable effect on that person that is used to taking 100mg of methadone every day?
Would the 20mg Kadian have a stronger effect than 20 mg of Methadone if I was to crush up the Kadian medicine so it will absorb all at once? Or is methadone so much stronger that not even crushing the Kadian will make it the same as methadone?
Thank you

meth addiction

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Written by Admin on July 31st, 2009 with 2 comments.
Read more articles on Methadone Uses.

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2 comments

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Get your own gravatar by visiting gravatar.com mercedesofladies36
#1. August 2nd, 2009, at 5:42 PM.

methadone….it killed anna nicole for christ sake as well as her son|!@

Get your own gravatar by visiting gravatar.com W W D
#2. August 3rd, 2009, at 10:35 PM.

It’s complicated on a number of points, so I wouldn’t advise a simple substitution. Roughly (very roughly) two thirds of morphine is “lost” to first-pass metabolism through the liver when taken orally, so the Kadian won’t be quite as much on a milligram-for-milligram basis, but the exact ratio is impossible to predict with good accuracy. Methadone 20 mg is roughly equivalent to 10 parenteral morphine, but again there’s lots of individual variation.

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